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Danny Alge publishes "Facile and efficient Lewis acid catalyzed synthesis of an asymmetric tetrazine useful for bio-orthogonal click chemistry applications" in Tetrahedron Letters

Alge figure

Danny Alge and his undergraduate researcher Dylan Donohue characterized the addition of a lewis acid catalyst (nickel) in the synthesis of a tetrazine molecule useful in click chemistry applications.

D.L. Alge, D.F. Donohue, and K.S. Anseth, "Facile and Efficient Lewis Acid Catalyzed Synthesis of an Asymmetric Tetrazine Useful for Bio-Orthogonal Click Chemistry Applications," Tetrahedron Letters (2013).